Heart and Neural Crest Derivatives Expressed 2 (HAND2) Peptide
HAND2
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN937519
Aperçu rapide pour Heart and Neural Crest Derivatives Expressed 2 (HAND2) Peptide (ABIN937519)
Antigène
HAND2
(Heart and Neural Crest Derivatives Expressed 2 (HAND2))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- DQNGEAEAFK AEIKKTDVKE EKRKKELNEI LKSTVSSNDK KTKGRTGWPQ
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of Hand2 antibody,
Alternative Names: Hand2 control peptide, Hand2 antibody Blocking Peptide, Anti-Hand2 Blocking Peptide, heart and neural crest derivatives expressed transcript 2 Blocking Peptide, AI225906 Blocking Peptide, AI661148 Blocking Peptide, Ehand2 Blocking Peptide, Hed Blocking Peptide, Th2 Blocking Peptide, Thing2 Blocking Peptide, bHLHa26 Blocking Peptide, dHAND Blocking Peptide, Hand2, Hand-2, Hand 2, Hand-2 Blocking Peptide, Hand 2 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))
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Sujet
- Hand2 is essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. It is required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. It plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Hand2 is involved in the development of branchial arches, which give rise to unique structures in the head and neck.
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Poids moléculaire
- 24 kDa
Antigène
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